Short description Lotrimin cream (Clotrimazole) is an anti-fungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and miconazole (Micatin, Monistat). It prevents growth of several types of fungi by preventing production of the membranes that surround fungal cells. It is used topically on the skin, inserted vaginally or allowed to dissolve in the mouth for local fungal infections.
