| Short description Aciphex (Rabeprazole) is a Proton Pump Inhibitor (PPI) used to treat Gastroesophageal Reflux Disease (GERD), ulcers, erosive esophagitis, or zollinger-ellison syndrome. Aciphex works by blocking acid production in the stomach. It may be used in combination with antibiotics including amoxicillin or clarithromycin to treat certain types of ulcers. It may also be used to treat other conditions as determined by your doctor.
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